Jian Yang Selected Research

Small Interfering RNA (siRNA)

12/2019	Expression profile-based screening for critical genes reveals S100A4, ACKR3 and CDH1 in docetaxel-resistant prostate cancer cells.
10/2017	Melatonin protects against the pathological cardiac hypertrophy induced by transverse aortic constriction through activating PGC-1β: In vivo and in vitro studies.
8/2017	Genistein Protects Against Ox-LDL-Induced Inflammation Through MicroRNA-155/SOCS1-Mediated Repression of NF-ĸB Signaling Pathway in HUVECs.
10/2016	Downregulation of Renal G Protein-Coupled Receptor Kinase Type 4 Expression via Ultrasound-Targeted Microbubble Destruction Lowers Blood Pressure in Spontaneously Hypertensive Rats.
3/2016	Pro-atherogenic role of smooth muscle Nox4-based NADPH oxidase.
10/2015	Reduced silent information regulator 1 signaling exacerbates myocardial ischemia-reperfusion injury in type 2 diabetic rats and the protective effect of melatonin.
1/2014	HIF-1α signaling activation by post-ischemia treatment with astragaloside IV attenuates myocardial ischemia-reperfusion injury.
1/2014	Doxorubicin Inhibits Proliferation of Osteosarcoma Cells Through Upregulation of the Notch Signaling Pathway.
4/2013	Yin Yang 1 promotes hepatic gluconeogenesis through upregulation of glucocorticoid receptor.
3/2013	Inhibition of farnesyl pyrophosphate synthase attenuates angiotensin II-induced cardiac hypertrophy and fibrosis in vivo.

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Jian Yang Research Topics

Disease

232	Neoplasms (Cancer) 11/2022 - 03/2003
87	Inflammation (Inflammations) 01/2023 - 05/2007
46	Infections 01/2023 - 09/2003
39	Hypertension (High Blood Pressure) 11/2022 - 12/2003
38	Reperfusion Injury 08/2022 - 01/2008
37	Myocardial Ischemia (Ischemic Heart Diseases) 05/2022 - 06/2007
37	Fibrosis (Cirrhosis) 01/2022 - 09/2007
35	Myocardial Infarction 03/2022 - 08/2002
35	Hepatocellular Carcinoma (Hepatoma) 01/2022 - 12/2008
31	Neoplasm Metastasis (Metastasis) 04/2022 - 02/2011
29	Wounds and Injuries (Trauma) 02/2023 - 01/2007
29	Cardiovascular Diseases (Cardiovascular Disease) 12/2021 - 06/2007
27	Atherosclerosis 01/2021 - 08/2002
26	Alzheimer Disease (Alzheimer's Disease) 06/2022 - 12/2014
24	Breast Neoplasms (Breast Cancer) 05/2021 - 07/2006
23	Pain (Aches) 08/2022 - 01/2011
23	Carcinogenesis 01/2022 - 07/2006
22	Ischemia 05/2021 - 01/2007
16	Stomach Neoplasms (Stomach Cancer) 01/2022 - 11/2009
16	Infarction (Infarctions) 12/2021 - 10/2009
16	Osteosarcoma (Osteogenic Sarcoma) 12/2021 - 01/2014
15	Heart Failure 01/2022 - 01/2013
15	Hypoxia (Hypoxemia) 01/2021 - 07/2010
14	Stroke (Strokes) 03/2022 - 12/2006
14	Schizophrenia (Dementia Praecox) 03/2022 - 09/2013
14	COVID-19 03/2022 - 01/2020
13	Hemorrhage 02/2023 - 11/2012
13	Lung Neoplasms (Lung Cancer) 04/2022 - 01/2004
13	Thrombosis (Thrombus) 03/2022 - 04/2008
13	Necrosis 01/2022 - 12/2007
13	Body Weight (Weight, Body) 01/2022 - 12/2006
13	Diabetes Mellitus 01/2022 - 09/2004
13	Pancreatic Neoplasms (Pancreatic Cancer) 01/2022 - 05/2012
13	Virus Diseases (Viral Diseases) 11/2021 - 06/2011
13	Obesity 01/2021 - 07/2012
12	Neuralgia (Stump Neuralgia) 08/2022 - 01/2011
12	Parkinson Disease (Parkinson's Disease) 02/2021 - 03/2006
12	Cardiomegaly (Heart Hypertrophy) 01/2021 - 06/2007
11	Carcinoma (Carcinomatosis) 01/2020 - 11/2006
10	Coronary Artery Disease (Coronary Atherosclerosis) 01/2022 - 10/2014
10	Colorectal Neoplasms (Colorectal Cancer) 01/2022 - 06/2008
10	Tuberculosis (Tuberculoses) 09/2021 - 01/2004
10	Prostatic Neoplasms (Prostate Cancer) 07/2021 - 09/2008
10	Hyperplasia 05/2020 - 12/2006
9	Adenocarcinoma 05/2022 - 01/2007
9	Rheumatoid Arthritis 01/2022 - 05/2007
9	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2022 - 06/2012
9	Glioma (Gliomas) 11/2021 - 09/2010
9	Liver Neoplasms (Liver Cancer) 01/2021 - 12/2014
9	Hyperglycemia 01/2021 - 11/2004
9	Hypertrophy 01/2020 - 01/2013
9	Neointima 01/2020 - 08/2004
8	Major Depressive Disorder (Major Depressive Disorders) 01/2022 - 01/2019

Drug/Important Bio-Agent (IBA)

93	Proteins (Proteins, Gene)FDA Link 08/2022 - 09/2007
65	Pharmaceutical PreparationsIBA 01/2023 - 09/2010
58	Biomarkers (Surrogate Marker)IBA 05/2022 - 08/2006
41	MicroRNAs (MicroRNA)IBA 09/2022 - 06/2007
36	Messenger RNA (mRNA)IBA 06/2022 - 01/2008
32	Biological ProductsIBA 07/2022 - 05/2008
30	CytokinesIBA 02/2023 - 09/2007
23	Glucose (Dextrose)FDA LinkGeneric 01/2023 - 11/2004
23	Peptides (Polypeptides)IBA 10/2021 - 10/2007
22	Long Noncoding RNAIBA 04/2022 - 01/2016
22	LipidsIBA 01/2022 - 12/2006
20	EnzymesIBA 01/2022 - 10/2009
18	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2021 - 12/2003
17	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 01/2004
17	Therapeutic UsesIBA 01/2022 - 07/2008
15	CollagenIBA 02/2023 - 05/2007
14	Small Interfering RNA (siRNA)IBA 12/2019 - 07/2009
13	RNA (Ribonucleic Acid)IBA 09/2022 - 02/2013
13	Interleukin-6 (Interleukin 6)IBA 05/2022 - 09/2007
12	AntigensIBA 01/2022 - 01/2007
12	koumineIBA 09/2021 - 05/2012
12	AlkaloidsIBA 06/2021 - 05/2007
11	AntioxidantsIBA 02/2022 - 01/2013
11	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 12/2021 - 01/2014
11	Analgesics (Analgesic Drugs)IBA 01/2021 - 01/2011
10	Transcription Factors (Transcription Factor)IBA 07/2022 - 02/2015
10	Angiotensin IIIBA 04/2022 - 10/2009
10	Anti-Bacterial Agents (Antibiotics)IBA 12/2021 - 09/2003
10	LigandsIBA 01/2021 - 01/2011
9	Doxorubicin (Adriamycin)FDA LinkGeneric 06/2022 - 01/2014
9	PolymersIBA 01/2022 - 06/2011
9	AlbuminsIBA 08/2021 - 05/2004
9	HMGB1 Protein (HMG1)IBA 05/2021 - 12/2010
9	Phosphotransferases (Kinase)IBA 01/2021 - 11/2005
8	Amyloid (Amyloid Fibrils)IBA 06/2022 - 12/2014
8	Protein Kinases (Protein Kinase)IBA 05/2022 - 03/2013

Therapy/Procedure

122	Therapeutics 11/2022 - 07/2006
28	Drug Therapy (Chemotherapy) 01/2022 - 11/2005
17	Hepatectomy 01/2022 - 04/2009
14	Stents 03/2022 - 12/2006
12	Chinese Traditional Medicine (Traditional Chinese Medicine) 01/2022 - 02/2014
12	Immunotherapy 01/2022 - 01/2007
10	Precision Medicine 11/2022 - 04/2013
9	Liver Transplantation 01/2022 - 09/2009
9	Aftercare (After-Treatment) 01/2019 - 11/2006
8	Radiotherapy 06/2022 - 01/2017
8	Transplantation 01/2022 - 06/2007